Gene Therapy as a Promising Approach for the Underlying Causes of Autism Spectrum Disorder

Abstract

Autism spectrum disorder (ASD) is a range of developmental disorders characterized by impaired traits associated with three distinct domains: communication, social interaction, and stereotypic repetitive behavior. Although its etiology depends on various components, current research mainly focuses on the genetic factors that contribute to the development of ASD and its effects. A big treatment consideration is gene therapy, which has disease-modifying potential. This article provides an insight into the foundation of ASD and the leading gene therapies that aim to rescue impaired neurological behavior. It will discuss how certain genetic factors can have large contributions to ASD development and how scientists can go about targeting these for potential remedy.